The host Seminoles (19-6) got the better of the Gators (21-5) in their third meeting of the season.
Playing in front of a crowd of 10,078, Florida took an early 2-0 lead on an RBI double in the first and a sacrifice fly in the third from Mike Zunino off of FSU starter Hunter Scantling.
FSU answered back in the bottom of the fourth as James Ramsey tied the score with a two-run double to right field that scored Mike McGee and Sherman Johnson.
Jayce Boy gave FSU a 3-2 lead in the fifth inning on a pop fly that UF second baseman Josh Adams missed. Ramsey scored on the play.
Stuart Tapley provided FSU with two insurance runs in the bottom of the eighth with a two-run home run to right field.
Scott Sitz (3-1) earned his third victory of the year after a scoreless sixth inning of relief.
McGee earned his fourth save of the season